Eukaryotic Gene Regulation | Principles of Biology from Nature Education

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The nucleosome. Digital model of a nucleosome, the fundamental structural unit of chromosomes in the eukaryotic cell nucleus, derived from X-ray crystallography data. Each nucleosome consists of a core group of histone proteins (orange) wrapped in chromosomal DNA (green). The nucleosome is a structure responsible for regulating genes and condensing DNA strands to fit into the cell's nucleus. Researchers once thought that nucleosomes regulated gene activity through their histone tails, but a 2010 study revealed that the structures' core also plays a role. The finding sheds light on how gene expression is regulated and how abnormal gene regulation can lead to cancer. Kenneth Eward/Science Source.

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تاریخ انتشار 2014